Tag: Expert Perspectives

inDemic Livestream: The State of Vaccine Confidence

Join inDemic Foundation Director Dr. Sam Sun and Professor Bernice Hausman of Penn State University’s College of Medicine for a discussion about vaccine hesitancy. A substantial portion of the population may be hesitant about receiving the COVID-19 vaccine. Dr. Sun and Dr. Hausman will offer insight into the rational, emotional and social factors that may be influencing the decision-making process—and what will happen if too many people refuse the vaccine.

Vaccine Hesitancy with Dr. Abram Wagner

In this video interview, we discuss vaccine hesitancy, first in measles as a historical backdrop, then for a potential or soon-to-be FDA authorized COVID-19 vaccine. Dr. Abram Wagner, research assistant professor of epidemiology at the University of Michigan, joins us to discuss recent research on vaccine hesitancy. His research looks at evidence-based programs and policies to control vaccine-preventable diseases. He currently holds a grant from the National Science Foundation that looks at behaviors and acceptance of a COVID-19 vaccine over time and across several regions, including the United States, India, and Taiwan. 

SARS-CoV-2 Evolution and Genetics with Dr. Niema Moshiri

In this video interview, we are joined by Dr. Niema Moshiri, assistant teaching professor of computer science & engineering at the University of California, San Diego (UCSD). He discusses how scientists are using the genetic sequences of SARS-CoV-2 to study viral transmission patterns and the evolution of the SARS-CoV-2 virus. He currently holds a grant from the National Science Foundation to develop novel software and hardware systems that can quickly analyze massive amounts of genetic data from COVID-19 labs around the world. 

1st and 2nd-generation COVID-19 Vaccines with Dr. Deborah Fuller

In this video interview, we discuss the strengths and limitations of COVID-19 vaccine candidates with Dr. Deborah Fuller, Professor of Microbiology at University of Washington. Her lab, which studies influenza, HIV, and Zika virus, is currently focused on immunity against COVID-19 and the development of novel vaccination strategies against SARS-CoV-2. Her lab’s work has resulted in over a dozen patents and two startup biotech companies. 

Perspectives on WHO’s SOLIDARITY Trial: Disappointing Findings Limit Remdesivir’s Use in COVID-19 Patients

| Sam Sun |

Last week, the World Health Organization (WHO) published data from its SOLIDARITY trial on a preprint server. The SOLIDARITY trial is a global, pragmatic, adaptive, master protocol trial investigating 4 therapies for hospitalized COVID-19 patients, including remdesivir. Disappointing findings for remdesivir in the SOLIDARITY trial elicited a statement from Gilead Sciences, questioning the validity of SOLIDARITY, and emphasizing its ACTT-1 trial as the “gold standard” regarding remdesivir’s value for COVID-19.

Expert Perspectives: Thromboembolic Disease in COVID-19

As part of an ongoing series of “Expert Perspectives”, Dr. Leon Henderson-MacLennan, Medical Advisor to inDemic Foundation and inThought Research, discusses the role of thromboembolic disease in COVID-19, and its implications for developmental therapeutics. Dr. Leon Henderson-MacLennan describes the rationale for conducting randomized, placebo-controlled trials on anticoagulants and anticomplement agents for COVID-19 associated thromboembolic disease, and highlights several agents and mechanisms of action to watch closely.

Expert Perspectives: Q&A on Actemra’s phase 3 EMPACTA study

| Bob Dickson |

In the first of an ongoing series of “Expert Perspectives” with members of inDemic Foundation’s scientific advisory board, we discuss data from EMPACTA, a randomized, double-blind, placebo-controlled phase 3 trial evaluating the efficacy and safety of Roche’s Actemra (tocilizumab) in hospitalized patients with COVID-19 pneumonia (NCT04372186). Actemra is one of several IL-6 inhibitors that’s been evaluated for patients with COVID-19.  At the time of this writing, data from EMPACTA has not been published in a peer-reviewed journal, but some of its key findings have been released by Roche/Genentech.  

© 2020 inDemic Foundation. All Rights Reserved.